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BestVitamin Best Methylfolate 1mg, Gluten-Free, Non-GMO, 60 Vegetable Capsules Pain and Fever Relief and functions as a leadBestVitamin Best Methylfolate (1mg) Science based Active Folic Acid (5 MTHF) BestVitamin Best Methylfolate is an active form of folic acid. Many individuals have intestinal or liver dysfunction, which makes the conversion of Folic Acid to Methylfolate very difficult or impossible. A deficiency of folic acid has been linked to low birth weight infants and neural tube defects, which is why the Centers for Disease Control recommends folic acid